AI Article Synopsis
- - Ameloblastoma is a rare, benign tumor that arises from the dental lamina, often appearing in the jaw, with mandibular cases being more common than those in the posterior maxilla.
- - A 46-year-old Malay man experienced swelling and other symptoms, leading to imaging that revealed a large cystic lesion in his left maxillary sinus, diagnosed as multicystic ameloblastoma after biopsy.
- - He underwent surgery to remove the tumor and received postoperative treatment; currently, he has no signs of recurrence and is being monitored annually.
Article Abstract
Ameloblastoma is a rare odontogenic tumour that develops from the epithelial remains of the dental lamina. It is a benign but locally aggressive neoplasm that typically manifests as slow-growing tumours in the jaw, with posterior maxilla ameloblastoma being the rarer occurrence compared to mandibular ameloblastoma. This case report is about a 46-year-old Malay man who presented with a two-month history of left palatal and cheek swelling, along with symptoms such as left eye blurring, nasal block, and dysphagia. Imaging revealed a massive cystic lesion in the left maxillary sinus, which was diagnosed as a multicystic ameloblastoma after biopsy. The patient underwent surgical resection with a partial maxillectomy and was treated postoperatively with antibiotics, steroids, and regular follow-up appointments. The histopathological examination confirmed the diagnosis, and the patient was given a dental obturator to cover the defect intraorally. He is currently under annual surveillance with no signs or symptoms of recurrence.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11468840 | PMC |
| http://dx.doi.org/10.7759/cureus.69165 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mandibular Reconstruction With a Patient-Specific Implant Following Surgical Excision of an Acanthomatous Ameloblastoma in a Dog.
J Vet Dent
January 2025
Department of Dentistry, Oral and Maxillo-facial Surgery, Eastcott Veterinary Referrals, Part of Linnaeus Group, Swindon, UK.
Canine acanthomatous ameloblastoma (CAA) is an invasive benign epithelial odontogenic tumour most commonly affecting the mandible of large breed dogs. To the author's knowledge, this report describes the first computer-aided design patient-specific implant (PSI) that has been placed for a critical sized bone defect in mandibular reconstruction of a dog in the UK. The aim was to restore mandibular stability using a regenerative approach combining a titanium locking plate and compression-resistant matrix infused with recombinant human bone morphogenetic protein-2 (rhBMP-2) to bridge the 85 mm mandibular defect created by a segmental mandibulectomy.
View Article and Find Full Text PDFExploring the debates surrounding keratoameloblastoma: An in-depth review of an emerging entity.
Semin Diagn Pathol
January 2025
King George's Medical University Faculty of Dental Sciences, India. Electronic address:
Ameloblastoma is a benign odontogenic epithelial tumor characterized by its aggressive behavior and a high likelihood of local recurrence if not fully excised. Ameloblastomas are a common type of slow-growing, true jaw tumor which may present as solid, multicystic or unicystic forms and originate from odontogenic epithelium and exhibit a variety of histological patterns. Keratoameloblastoma is considered to be a rare variant of ameloblastoma associated with more intense keratinization.
View Article and Find Full Text PDFThe expression of Methyltransferase-like 3 in dentigerous cyst and ameloblastoma.
J Clin Exp Dent
December 2024
Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, Srinakharinwirot University.
Background: N6-methyladenosine (m6A), the most abundant internal RNA modification in mammals, plays a critical role in many forms of cancer. Methyltransferase-like 3 (METTL3) serves as the main catalytic subunit of the m6A writer and plays a role in the progression of head and neck squamous cell carcinoma. To date, the role of METTL3 in odontogenic lesions has never been investigated.
View Article and Find Full Text PDFBcl-2 and galectin-3 expression is associated with recurrence of ameloblastoma.
Dent Res J (Isfahan)
December 2024
Department of Restorative Dentistry, College of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.
Background: Ameloblastoma is a benign odontogenic neoplasm with a high recurrence rate. Identifying cellular and molecular changes in this neoplasm may help predict the recurrence risk. Bcl-2 and galectin-3 are anti-apoptotic proteins associated with the prognosis of many neoplasms.
View Article and Find Full Text PDFFrom pathogenesis to precision medicine: Transformative advances in research and treatment of ameloblastoma.
Cancer Lett
January 2025
Department of Oral and Maxillofacial & Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai, China. Electronic address:
Odontogenic neoplasms of the jaw are dominated by ameloblastoma (AM), a locally aggressive epithelial tumor with a significant propensity for recurrence. The World Health Organization's 2022 update to the AM classification system underscores recent progress in comprehending its underlying mechanisms and refining clinical approaches. Contemporary research has yielded significant insights into the genetic underpinnings of AM, paving the way for the development of precision-based treatment strategies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!