The primary challenge in diagnosing ocular diseases in canines based on images lies in developing an accurate and reliable machine learning method capable of effectively segmenting and diagnosing these conditions through image analysis. Addressing this challenge, the study focuses on developing and rigorously evaluating a machine learning model for diagnosing ocular diseases in canines, employing the U-Net neural network architecture as a foundational element of this investigation. Through this extensive evaluation, the authors identified a model that exhibited good reliability, achieving prediction scores with an Intersection over Union (IoU) exceeding 80 %, as measured by the Jaccard index. The research methodology encompassed a systematic exploration of various neural network backbones (VGG, ResNet, Inception, EfficientNet) and the U-Net model, combined with an extensive model selection process and an in-depth analysis of a custom training dataset consisting of historical images of different medical symptoms and diseases in dog eyes. The results indicate a fairly high degree of accuracy in the segmentation and diagnosis of ocular diseases in canines, demonstrating the model's effectiveness in real-world applications. In conclusion, this potentially makes a significant contribution to the field by utilizing advanced machine-learning techniques to develop image-based diagnostic routines in veterinary ophthalmology. This model's successful development and validation offer a promising new tool for veterinarians and pet owners, enhancing early disease detection and improving health outcomes for canine patients.
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http://dx.doi.org/10.1016/j.heliyon.2024.e38287 | DOI Listing |
IDCases
January 2025
Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Leipzig University Medical Center, Leipzig, Germany.
An 18-year-old male patient from Ukraine, living in Germany for 2 years, presented with a painless subcutaneous swelling on the left cheek that had been present for several months. Finally, the diagnosis of subcutaneous dirofilariasis caused by was confirmed by 12S rRNA gene PCR and sequencing from tissue by nematode-specific PCRs followed by sequencing after surgical resection of the lesion. Microfilaremia was ruled out and no further treatment was required.
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January 2025
Parasitology and Mycology Center, Adolfo Lutz Institute, Sao Paulo, Brazil.
Visceral leishmaniasis (VL) is a zoonotic disease in which dogs are the main reservoirs. Until now, the serological tests do not present satisfactory sensitivity for diagnosis of these hosts. One of the functions of extracellular vesicles (EVs) is related to immunological host response.
View Article and Find Full Text PDFTrop Biomed
December 2024
Department of Veterinary Pathology & Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang, Malaysia.
Canine haemotrophic mycoplasmosis is caused by mycoplasma haemopathogens, which includes Mycoplasma haemocanis (Mhc) and Candidatus Mycoplasma haematoparvum (CMhp). The Mhc and CMhp pose a health risk to dogs, particularly in immunocompromised and splenectomised dogs, as they lead to haemolytic anaemia. There is scarce information on the detection of Mycoplasma in dogs in Malaysia.
View Article and Find Full Text PDFG3 (Bethesda)
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Canine Genetics Centre, Department of Veterinary Medicine, University of Cambridge, Cambridgeshire, CB3 0ES, UK.
Retinopathy with Vitamin E Deficiency (RVED) is a familial disease in the English Cocker Spaniel (ECS) dog breed. Ophthalmic abnormalities observed in RVED-affected ECS include lipofuscin granule deposition within the tapetal fundus and subsequent retinal degeneration resulting in visual deficits. Affected dogs may also exhibit neurological signs that include ataxia and hindlimb proprioceptive deficit.
View Article and Find Full Text PDFBio Protoc
January 2025
Department of Stomatology, Peking Union Medical College Hospital, Beijing, China.
Pulpitis is an important and prevalent disease within the oral cavity. Thus, animal models are necessary tools for basic research focused on pulpitis. Researchers worldwide often use dogs and miniature pigs to construct animal models of pulpitis.
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