AI Article Synopsis
- * PPP has shown pharmacological effects such as anti-tumor, liver protection, lipid reduction, and anti-inflammatory properties, but there's limited understanding of its structure, safety, and real-world applications.
- * This article reviews the extraction, purification, and biological activities of PPPs from different pine species, aiming to enhance understanding and encourage future research for therapeutic uses and biomaterial development.
Article Abstract
Pine pollen, a nutrient-rich pollen, is composed of significant amounts of protein, vitamins, and carbohydrates, featuring various functional groups. Pine pollen polysaccharide (PPP), a key bioactive component of pine pollen, exhibits a range of pharmacological activities, including anti-tumor, liver-protective, lipid-lowering, anti-inflammatory, immunomodulatory, antioxidant, hypoglycemic, antiviral, and antibacterial properties. While numerous extraction and purification techniques have successfully isolated and characterized PPPs, understanding of their structure-activity relationships, safety profiles, and practical applications remains limited. This hampers their full potential in utilization and development. In this article, we present a comprehensive overview of the extraction, purification, structure characteristics, structural-activity relationships, biological activities, and pharmaceutical applications of PPPs derived from various sources, including Pinus massoniana Lamb, Pinus tabuliformis Carr, and related species. This review aims to provide extensive knowledge and insights for future research and the application of PPPs as therapeutic agents and versatile biomaterials.
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| http://dx.doi.org/10.1016/j.ijbiomac.2024.136473 | DOI Listing |
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