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Acute hematogenous disseminated pulmonary tuberculosis and tuberculous meningitis following in vitro fertilization and embryo transfer: A case report.
IDCases
October 2024
Yunnan Provincial Infectious Disease Hospital, 28 km from Shi 'an Highway, Yunnan Province, China.
Article Synopsis
- Assisted reproductive technologies like IVF-ET can help infertile patients achieve pregnancy, but they may also lead to changes in the body that lower immune defenses, increasing the risk of tuberculosis (TB) infection.
- A case report highlights a patient with normal immune function who developed severe pulmonary tuberculosis following IVF-ET, emphasizing the potential dangers.
- The authors recommend screening for genital and latent TB before IVF-ET and advise healthcare providers to be alert for active TB symptoms during pregnancy, especially in the presence of unexplained fever, cough, or bleeding.
The use of antibiotic-loaded calcium sulphate beads in debridement, antibiotics, and implant retention (DAIR) for periprosthetic infections: a retrospective comparative cohort on outcome.
Acta Orthop
November 2024
Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Article Synopsis
- The study aimed to compare the effectiveness of calcium sulphate (CS) beads loaded with antibiotics in treating periprosthetic joint infections during debridement, antibiotics, and implant retention (DAIR) versus standard treatment without local antibiotics.
- A total of 176 patients were analyzed, with 102 receiving CS beads and 74 as a control group, and various infection types were assessed for reinfection and reoperation rates.
- The results showed no significant difference in infection-free and revision-free survival rates overall, but the use of CS beads did reduce reinfection and reoperation rates in cases of acute hematogenous infections.
Spondylodiscitis and Its Mimickers: A Pictorial Review.
Biomedicines
November 2024
Department of Radiology, National Institute for Infectious Disease "Lazzaro Spallanzani", 00149 Rome, Italy.
Spondylodiscitis is an infection of the intervertebral disc, the adjacent vertebral body, and/or contiguous structures due to the introduction of infectious agent, usually by the hematogenous route. Imaging is crucial in assessing bacterial and tubercular spondylodiscitis, as well as their associated complications. Magnetic resonance imaging in particular can clearly depict osteo-structural changes in the vertebral body and the associated disc, as well as any soft-tissue complications, such as paravertebral abscess and/or epidural abscess, improving disease characterization and helping to recognize the agent involved.
View Article and Find Full Text PDFA transformer-based deep learning model for identifying the occurrence of acute hematogenous osteomyelitis and predicting blood culture results.
Front Microbiol
November 2024
Department of Orthopaedics, Haicheng Bonesetting Hospital, Haicheng, Liaoning, China.
Background: Acute hematogenous osteomyelitis is the most common form of osteomyelitis in children. In recent years, the incidence of osteomyelitis has been steadily increasing. For pediatric patients, clearly describing their symptoms can be quite challenging, which often necessitates the use of complex diagnostic methods, such as radiology.
View Article and Find Full Text PDFA prospective multicentre study of 82 prosthetic joint infections treated with a standardised debridement and implant retention (DAIR) protocol followed by 6 weeks of antimicrobial therapy: favourable results.
Hip Int
January 2025
Division of Orthopaedic Surgery, Oslo University Hospital Ullevål, Oslo, Norway.
Introduction: Prosthetic joint infection (PJI) is a much-feared complication in total joint arthroplasty. Debridement, antibiotics, irrigation and implant retention (DAIR) is often the preferred treatment in acute PJIs, but with varying results. The primary aim of this study was to evaluate the outcome of a high quality DAIR procedure performed according to a consistently applied surgical protocol in early postoperative and acute haematogenous PJIs in hip and knee, and secondary to study risk factors associated with failure.
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