AI Article Synopsis
- Female fertility is essential for family well-being, but factors like chemotherapy and lifestyle changes can negatively affect it, highlighting the need for preservation and restoration efforts.
- Stem cells offer potential solutions through advancements in areas like ovarian tissue freezing, in vitro culture of ovarian tissue, and creating ovarian-like organs.
- The review discusses the importance of stem cell technology in fertility preservation, the need for interdisciplinary collaboration, and personalized treatment strategies for effective fertility solutions.
Article Abstract
The fertility of women is crucial for the well-being of individuals and families. However, various factors such as chemotherapy, lifestyle changes, among others, may lead to a decline in female fertility, thus emphasizing the significance of preserving and restoring fertility. Stem cells, with their unique capacity for self-renewal and pluripotent differentiation, have made significant strides in areas such as ovarian tissue cryopreservation, in vitro culture of frozen-thawed ovarian tissue, and construction of ovarian-like organs. This review aims to summarize the latest findings in these fields, highlighting the pivotal role, mechanisms, and future prospects of stem cell technology in preserving and restoring female fertility. Additionally, the importance of interdisciplinary collaboration is underscored, as personalized stem cell therapy regimens tailored through interdisciplinary cooperation between reproductive medicine and stem cell fields hold promise in providing reliable solutions for the preservation and restoration of female fertility.
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| http://dx.doi.org/10.1016/j.repbio.2024.100958 | DOI Listing |
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