Gateway to the study of the amygdala and emotion.

Cereb Cortex

Department of Neuroscience, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, United States.

Published: January 2025

AI Article Synopsis

  • The amygdala's role in processing emotions has gained attention in neuroscience due to new pathways for emotional information transmission.
  • Groundbreaking experiments in the 90s used rodent models to reveal the neural circuitry involved in emotional memory through various research techniques.
  • The development of these research tools allowed scientists to focus on the amygdala's connections, fueling extensive studies on its impact on emotional memory.

Article Abstract

The study of the amygdala and its role in the processing of emotions has become a common focus in neuroscience. The modern expansion of research in this area is partly due to the discovery of a subcortical pathway for the transmission of emotional information and the experimental paradigm that was developed to study it. Groundbreaking experiments during the 90s utilized anatomical, neurophysiological, and behavioral lesion studies in a rodent animal model to uncover the neural circuitry of a simple emotional memory. These studies demonstrated the essential role of a specific monosynaptic pathway in emotional memory, using traditional tools and behavioral methods. The development of an animal model with a simple and appropriate classical conditioning paradigm made experimental investigations into the neural basis of emotion tenable and available to a generation of neuroscientists. These tools and a focus on the amygdala's neural connections and their essential role in emotional memory were a driving force in the explosion of research regarding the amygdala and emotion.

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Source
http://dx.doi.org/10.1093/cercor/bhae408DOI Listing

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