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Functional neurological disorder in pregnancy, labour and the postpartum period: systematic review. | LitMetric

AI Article Synopsis

  • * Analysis of 36 studies revealed six subtypes of FND and showed that new cases were more frequent in the third trimester, with some patients receiving inappropriate treatments like anti-seizure medications.
  • * The authors emphasize the need for more prospective research to better understand the impact of FND on women's health during and after pregnancy.

Article Abstract

Aims And Method: Functional neurological disorder (FND) most often presents in women of childbearing age, but little is known about its course and outcomes during pregnancy, labour and postpartum (the perinatal period). We searched MEDLINE, PsycInfo and Embase combining search terms for FND and the perinatal period. We extracted data on patient demographics, subtype of FND, timing of symptom onset, comorbidities, medications, type of delivery, investigations, treatment, pregnancy outcomes and FND symptoms at follow-up.

Results: We included 36 studies (34 case reports and 2 case series) describing 43 patients. Six subtypes of FND were identified: functional (dissociative) seizures, motor weakness, movement disorder, dissociative amnesia, speech disorders and visual symptoms. New onset of perinatal FND was more common in the third trimester and onwards. Some women with functional seizures were exposed to unnecessary anti-seizure prescriptions and intensive care admissions.

Clinical Implications: Prospective studies are urgently needed to explore how FND interacts with women's health in the perinatal period.

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Source
http://dx.doi.org/10.1192/bjb.2024.70DOI Listing

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