AI Article Synopsis
- * Their chemical structures were determined using advanced techniques like spectroscopy and mass spectrometry, with absolute configurations confirmed through electronic circular dichroism calculations.
- * The new compounds were tested for their ability to kill cancer cells, showing that one compound was effective against three types of cancer cells (HT-29, A-549, and MCF-7), while the other was effective against only two (HT-29 and MCF-7).
Article Abstract
Two new guaiane-type sesquiterpene glycosides, atractylodes guaianoside I () and atractylodes guaianoside II (), along with eleven known sesquiterpenes (-), were isolated from Koidz. ex Kitam. The structures of these two new compounds were elucidated by extensive spectroscopic analyses and mass spectrometric techniques. And their absolute configurations were confirmed by electronic circular dichroism (ECD) calculations. In addition, the isolated compounds were evaluated for their cytotoxic activities against three cancer cell lines HT-29, A-549, and MCF-7. Results showed that new compound had inhibitory effects on three types of cancer cells, while new compound only had inhibitory effects on HT-29 and MCF-7.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2024.2413431 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!