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Exploring piscidin-1: a marine-derived antimicrobial peptide's potential in oral cancer treatment.
Nat Prod Res
October 2024
Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Expression of the Antimicrobial Peptide Piscidin 1 and Neuropeptides in Fish Gill and Skin: A Potential Participation in Neuro-Immune Interaction.
Mar Drugs
February 2022
Department of Veterinary Sciences, University of Messina, Polo Universitario dell'Annunziata, 98168 Messina, Italy.
Antimicrobial peptides (AMPs) are found widespread in nature and possess antimicrobial and immunomodulatory activities. Due to their multifunctional properties, these peptides are a focus of growing body of interest and have been characterized in several fish species. Due to their similarities in amino-acid composition and amphipathic design, it has been suggested that neuropeptides may be directly involved in the innate immune response against pathogen intruders.
View Article and Find Full Text PDFThe putative mature peptide of piscidin-1 modulates global transcriptional profile and proliferation of splenic lymphocytes in orange-spotted grouper (Epinephelus coioides).
Fish Shellfish Immunol
March 2019
Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanology, Shenzhen University, Shenzhen, Guangdong, 518055, PR China. Electronic address:
Piscidins are important components in protecting microbial infections in teleost. The present study purified and identified a truncated peptide, whose sequence was very close to that of putative mature peptide of epinecidin-1 (piscidin-1) in orange-spotted grouper (Epinephelus coioides), Epi-1 (also named as short form of ecPis-1, ecPis-1S). The immunomodulatory effects of ecPis-1S on splenic lymphocytes of orange-spotted grouper were explored in vitro.
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