AI Article Synopsis
- The study aimed to evaluate the safety and effectiveness of endoscopic subserosal dissection (ESSD) for treating upper gastrointestinal submucosal tumors, involving 16 patients from July 2018 to December 2021.
- Results showed that all patients had successful removal of tumors with no complications, achieving 100% en bloc and R0 resection rates, and tumors were primarily located in the corpus with an average size of 2.78 cm.
- Follow-up over 9 months indicated no recurrence or metastasis, suggesting that ESSD is a safe and effective option for curative treatment of these tumors in patients without metastasis.
Article Abstract
Objective: To investigate the safety and efficacy of endoscopic subserosal dissection for patients with submucosal tumors in the upper gastrointestinal tract.
Methods: This retrospective single-center study included 16 patients who underwent ESSD. All patients were enrolled from July 2018 to Dec 2021. Parameters such as demographics, size, resection margin, complications, pathological features, procedure time and follow-up were investigated and analyzed.
Results: Our study achieved 100% en bloc resection and 100% R0 resection. The most common location was the corpus with a mean tumor size of 2.78 ± 1.56 cm. The mean age, procedure time, were 53.4 ± 10.3 years, 85.31 ± 46.64 min respectively. Acocording to National Institutes of Health classification, 7 (13, 53.85%), 5 (13, 38.46%) ,and 1 (13, 7.69%) objects belonged to the very low, low, and intermediate classification, respectively. Immunohistochemistry results showed a 100% positive rate of CD34, DOG-1, CD117, and Ki67. A mean follow-up of 9.3 ± 2.5 months showed no recurrence or metastasis.
Conclusions: ESSD is effective and safe surgical procedure for curative removal of gastrointestinal submucosal tumors in the upper gastrointestinal tract, and it can be preferred for patients with no metastasis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11465777 | PMC |
| http://dx.doi.org/10.1186/s12893-024-02592-z | DOI Listing |
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