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A rare case of peritoneal tuberculosis mimicking peritoneal carcinomatosis: the ongoing challenge. | LitMetric

A rare case of peritoneal tuberculosis mimicking peritoneal carcinomatosis: the ongoing challenge.

BMC Infect Dis

Department of Internal Medicine, Kaiser Permanente, 9961 Sierra Ave, Fontana, Inland Empire, CA, 92395, USA.

Published: October 2024

AI Article Synopsis

  • Tuberculosis (TB) is a complex infection that can affect any part of the body, with many people unknowingly carrying it in a latent form, and there's an increasing number of abdominal TB cases.
  • Diagnosis is challenging due to overlapping symptoms with other conditions, especially in immunocompromised individuals, making early detection difficult.
  • A case study of a 71-year-old woman illustrates the difficulties in diagnosing peritoneal tuberculosis, which was mistaken for peritoneal carcinomatosis, highlighting the need for increased awareness and scrutiny in similar cases.

Article Abstract

Tuberculosis (TB) is a serious infection that can involve any organ system and present in various forms. About one-third of the world's population are carriers of latent TB. Although most cases are from a pulmonary origin, there is a rising prevalence of abdominal TB. Patients with pulmonary or extrapulmonary TB are treated similarly through the use of pharmacological therapy. Nonspecific clinical manifestations of TB have made it difficult for clinicians to diagnose. Peritoneal tuberculosis (PTB) is a serious concern as its symptoms overlap with that of many other chronic conditions, especially in those who are immunocompromised. The lack of highly sensitive and specific testing methods has made early intervention difficult, therefore a high index of suspicion is crucial in the progression of the disease. Here, we present a case of a 71-year-old female with a history of abdominal pain, fever, and weakness. Initial investigation with computed tomography (CT) imaging revealed omental fat stranding that pointed towards peritoneal carcinomatosis (PC) from possible recurrence of her ovarian cancer. Further investigation with a peritoneal biopsy was remarkable for caseating granulomas with fat necrosis confirming extrapulmonary TB. This report highlights a rare case of PTB mimicking PC in an elderly patient who is immunocompromised from the use of long-term corticosteroids who continued to decline after pharmacological treatment of the disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11468269PMC
http://dx.doi.org/10.1186/s12879-024-10028-5DOI Listing

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