AI Article Synopsis

  • The text discusses a subclinical infection in cattle that occasionally leads to cases of bovine encephalomyelitis, particularly in calves and European buffalo.
  • An outbreak in Brazil affected 3-month-old buffalo calves, showing symptoms like incoordination and depression, ultimately resulting in death.
  • Necropsies revealed severe brain and heart abnormalities along with specific immune responses, while tests showed no pathogenic bacteria present, confirming the disease through PCR.

Article Abstract

causes subclinical infections in cattle, but sporadic, bovine encephalomyelitis cases have been reported in calves and documented in two instances in European buffalo. An outbreak of -induced encephalomyelitis and serositis occurred in 3-month-old buffalo calves from Brazil. Initially presenting with pelvic limb incoordination, the calves progressed to lateral recumbency, depression, and death. Necropsies of two calves revealed encephalomyelomalacia, fibrin deposition on the external surface of the pericardium (case 1) and pleural and pericardial fibrosis (case 2). Microscopically, a multifocal to coalescing, necrotizing, neutrophilic and lymphocytic meningoencephalomyelitis with fibrinoid vasculitis and thrombosis was present. Anti- antibody labeling was demonstrated by immunohistochemistry. Bacteriological examination yielded no pathogenic bacteria in the brain or lungs. was confirmed by PCR. This work describes the gross, histopathological, microbiological, and molecular findings in two cases from an outbreak of -induced disease in buffalo calves.

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http://dx.doi.org/10.1177/03009858241288116DOI Listing

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