AI Article Synopsis
- Acute pulmonary embolism (PE) is the third leading cause of heart-related deaths, primarily due to acute right ventricular failure associated with it.
- Despite advancements in treatment methods like endovascular devices and specialized healthcare teams, many patients with severe PE continue to face high mortality rates.
- This review focuses on modern treatment strategies, including surgery and interventional techniques, as well as the use of mechanical circulatory support for patients experiencing hemodynamic compromise from PE.
Article Abstract
Acute pulmonary embolism (PE) represents the third leading cause of cardiovascular mortality, with most PE-related mortality associated with acute right ventricular (RV) failure. Despite an increase in attention to acute PE with new endovascular devices for therapy and the adoption of multidisciplinary clinical treatment teams, mortality rates remain high in patients who present with PE-related hemodynamic compromise. Currently, the advanced treatment modalities for acute high-risk and intermediate high-risk PE are limited to several interventional modalities-open surgical embolectomy and systemic fibrinolytic agents. The purpose of this state-of-the-art review is to describe modern therapeutic techniques and strategies (both interventional and surgical) and the role of mechanical circulatory support (MCS) for hemodynamic compromise in PE.
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| http://dx.doi.org/10.1016/j.cardfail.2024.07.012 | DOI Listing |
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