AI Article Synopsis
- Secondary mitral regurgitation (SMR) increases the risk of mortality and heart failure hospitalizations, necessitating a collaborative approach for patient management.
- While guideline-directed medical therapies are essential, some patients experience persistent SMR, leading to the adoption of transcatheter edge-to-edge repair (TEER) to enhance survival.
- Advancements in technology and operator skills have improved the safety and efficacy of TEER, with ongoing research into new devices offering additional treatment options for patients who aren't candidates for TEER.
Article Abstract
Secondary mitral regurgitation (SMR) is associated with increased mortality and heart failure hospitalizations. The management of heart failure patients with SMR is complex and requires a multidisciplinary Heart Team approach. Guideline-directed medical therapies remain fundamental, yet in a proportion of patients SMR persists. In the past decade, transcatheter edge-to-edge repair (TEER) has been shown to improve survival in patients with SMR who remain symptomatic despite medical therapy. Technical advancements across newer generations of devices, improved imaging, and greater operator expertise have collectively contributed to the increased safety and efficacy of this procedure over time. Various emerging transcatheter mitral valve repair and replacement devices are currently under investigation and may offer superior, complementary or synergistic treatment options in patients ineligible for TEER. This review provides a state-of-the-art overview regarding the diagnosis of SMR, and currently available transcatheter mitral valve interventions and describes a contemporary approach to the management of SMR.
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| http://dx.doi.org/10.1016/j.cardfail.2024.06.018 | DOI Listing |
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