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Real-World Studies of Biologics for the Treatment of Moderate-to-Severe Asthma. | LitMetric

Real-World Studies of Biologics for the Treatment of Moderate-to-Severe Asthma.

Immunol Allergy Clin North Am

Division of Allergy& Immunology, Department of Medicine, UMDNJ-Rutgers, 110 Bergen Street Suite 1, Newark, NJ 07103, USA.

Published: November 2024

AI Article Synopsis

  • - There are currently 6 biologic agents approved for asthma treatment, all of which have been tested in strict clinical trials.
  • - The rigid criteria used in these trials may not reflect how effective the treatments are in the real world.
  • - This review examines real-world data on biologics for asthma, emphasizing indicators that can help predict how well patients might respond to these therapies.

Article Abstract

Presently, there are 6 biologic agents available for treatment of asthma. Each of these agents has undergone robust clinical trials in their approval programs. Such studies rely upon very rigid entry criteria that may not translate to real-world efficacy. Thus, exploring the efficacy of these agents in a larger, more heterogeneous, population brings a sense of comfort regarding their efficacy in the real-world. This review explores the available literature regarding the use of biologics in the real world, with a focus on markers of likely response to therapy.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.iac.2024.07.007DOI Listing

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