Introduction And Importance: Gorham syndrome, or Gorham-Stout disease, is a rare disorder characterized by spontaneous and persistent bone resorption without any known cause, leading to severe complications [2]. The clinical presentation of this condition varies widely, complicating efforts in diagnosis and treatment. In our case report, we present the story of an 88-year-old woman who bravely and gracefully faced the challenges caused by Gorham syndrome. Despite prior treatments, her condition worsened, emphasizing the need for tailored approaches.

Case Presentation: The patient's symptoms extended to bilateral shoulders, affecting daily living. Physical examination revealed tenderness, swelling, and muscle wasting. Her blood investigation showed vitamin D deficiency and imaging confirmed complete humeral head resorption.

Case Discussion: Her case highlights the limitations of standard therapies. Variable presentations underscore the importance of thorough evaluation. Radiographic evidence revealed severe bone destruction, emphasizing the disability caused by Gorham syndrome.

Conclusion: Recognition of the disease as early as possible, correct diagnosis, and effective management are essential. This patient's story highlights the importance of the multi-faceted treatment approach for patients with Gorham Syndrome: medical treatment, supportive care, compassion, and tenacity to improve the quality of life.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562405PMC
http://dx.doi.org/10.1016/j.ijscr.2024.110407DOI Listing

Publication Analysis

Top Keywords

gorham syndrome
12
caused gorham
8
"unraveling rare
4
rare encounter
4
encounter gorham's
4
gorham's disease
4
disease 88-year-old
4
88-year-old female"
4
female" introduction
4
gorham
4

Similar Publications

Introduction And Importance: Gorham syndrome, or Gorham-Stout disease, is a rare disorder characterized by spontaneous and persistent bone resorption without any known cause, leading to severe complications [2]. The clinical presentation of this condition varies widely, complicating efforts in diagnosis and treatment. In our case report, we present the story of an 88-year-old woman who bravely and gracefully faced the challenges caused by Gorham syndrome.

View Article and Find Full Text PDF

The spontaneous disappearance of a segment of bone in a short period without the existence of a tumoral disease that justifies it is an exceptional event. We report the case of an older adult in whom the upper epiphysis of the right humerus and part of the acromion disappeared in a period of 3 weeks in the absence of a malignant tumor. Bone biopsy revealed osteoclasts, lymphatic vessels, and blood vessels.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the use of telehealth in pediatric primary care during the COVID-19 pandemic, highlighting variations based on community social determinants and individual social needs.
  • - Analyzing 107,629 patient encounters from March 2020 to July 2020, the researchers found that children in higher-opportunity neighborhoods continued to utilize services more than those in lower-opportunity areas.
  • - The findings indicate that while telehealth provided access to care for children with reported social needs, it didn't fully eliminate challenges faced by those in disadvantaged communities.
View Article and Find Full Text PDF

Trisomy 21 (T21), a recurrent aneuploidy occurring in 1:800 births, predisposes to congenital heart disease (CHD) and multiple extracardiac phenotypes. Despite a definitive genetic etiology, the mechanisms by which T21 perturbs development and homeostasis remain poorly understood. We compared the transcriptome of CHD tissues from 49 patients with T21 and 226 with euploid CHD (eCHD).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!