AI Article Synopsis
- A case of pancreatic ductal adenocarcinoma exhibited high 68Ga-DOTATATE uptake, which is typically associated with neuroendocrine tumors, during a PET/CT scan.
- Immunohistochemical analysis revealed that the tumor cells did not have somatostatin receptor subtype 2, while the surrounding nonneoplastic islets were positive for this receptor.
- This finding suggests that pancreatic ductal adenocarcinoma should be considered in the differential diagnosis when encountering pancreatic lesions with increased 68Ga-DOTATATE uptake.
Article Abstract
We present a case of pancreatic ductal adenocarcinoma showing increased 68 Ga-DOTATATE uptake mimicking neuroendocrine tumor on PET/CT. Immunohistochemical analyses of the resected tumor showed the tumor cells were negative for somatostatin receptor subtype 2. The nonneoplastic islets scattered throughout the tumor were positive for somatostatin receptor subtype 2, which may be responsible for the increased 68 Ga-DOTATATE uptake. This case indicates that pancreatic ductal adenocarcinoma should be included in the differential diagnosis of the pancreatic lesions showing increased 68 Ga-DOTATATE uptake.
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| http://dx.doi.org/10.1097/RLU.0000000000005452 | DOI Listing |
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