AI Article Synopsis
- - Hybrid [F]FDG PET imaging is the preferred method for diagnosing infectious and inflammatory disorders, with recent updates in clinical guidelines reflecting a surge in evidence-based research since 2013.
- - The aim of the updated guidelines is to furnish physicians with current, evidence-based knowledge to effectively conduct and interpret hybrid [F]FDG PET scans in adult patients.
- - A systematic literature review revealed that hybrid [F]FDG PET is highly effective for managing these conditions, although monitoring treatment response remains a challenging area due to limited research.
Article Abstract
Introduction: Hybrid [F]FDG PET imaging is currently the method of choice for a wide variety of infectious and inflammatory disorders and was recently adopted in several clinical guidelines. A large amount of evidence-based articles, guidelines and appropriate use criteria have been published since the first version of this guideline in 2013.
Purpose: To provide updated evidence-based information to assist physicians in recommending, performing and interpreting hybrid [F]FDG PET examinations for infectious and inflammatory disorders in the adult population.
Methods: A systematic literature search of evidence-based articles using whole-body [F]FDG hybrid imaging on the indications covered within this guideline was performed. All systematic reviews and meta-analyses published within the last 10 years until January 2023 were identified in PubMed/Medline or Cochrane. For each indication covered in this manuscript, diagnostic performance was provided based on meta-analyses or systematic reviews. If not available, results from prospective or retrospective studies were considered based on predefined selection criteria. RESULTS AND CONCLUSIONS: Hybrid [F]FDG PET is extremely useful in the work-up and management of adults with infectious and inflammatory diseases, as supported by extensive and rapidly growing evidence-based literature and adoption in clinical guidelines. Practical recommendations are provided describing evidence-based indications as well as interpretation criteria and pitfalls. Monitoring treatment response is the most challenging but insufficiently studied potential application in infection and inflammation imaging.
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| http://dx.doi.org/10.1007/s00259-024-06915-3 | DOI Listing |
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