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Clinical Manifestations and Challenges in Adolescent and Adult Females With Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.
J Clin Endocrinol Metab
January 2025
Department of Women's and Children's Health, Karolinska Institutet, SE-171 76 Stockholm, Sweden.
Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) is a rare genetic condition that results in cortisol deficiency and excess production of adrenal androgens. While the introduction of newborn screening for CAH has reduced morbidity and mortality, management of CAH remains challenging. Lifelong treatment with glucocorticoids is required to replace the endogenous cortisol deficiency and reduce excess adrenal androgens.
View Article and Find Full Text PDFImpact of socioeconomic and political stressors on mental health: a cross-sectional study on university students in Lebanon.
BMC Med Educ
January 2025
Department of Chemistry, American University of Beirut, Beirut, 1107-2020, Lebanon.
A cross-sectional study was conducted investigating the association between exposure to financial, political, academic and social stressors, and symptoms of depression, anxiety and burnout among university students in Lebanon. Lebanon is a developing country experiencing a financial crisis and sociopolitical turmoil with poorly characterized impacts on the mental health of residents. To assess burnout and symptoms of depression, anxiety, a condensed version of the Malach-Pines Burnout Measure and the Patient Health Questionnaire-4 (PHQ-4) were used, respectively.
View Article and Find Full Text PDFThe Impact of Leadership Training on Burnout and Fulfillment Among Direct Reports.
J Healthc Manag
January 2025
Department of Obstetrics and Gynecology, MedStar Washington Hospital Center, Washington, DC.
Goal: Burnout, decreased professional fulfillment, and resultant attrition across the medical professions are increasingly recognized as threats to sustainable and cost-effective healthcare delivery. While the skill level of leaders as perceived by their direct reports has been correlated with rates of burnout and fulfillment, no studies, to our knowledge, have directly evaluated whether intervention via leadership training impacts burnout and fulfillment among direct reports. The goal of this study was to evaluate the effectiveness of a leadership training intervention on direct reports' perceptions of the leadership skills of supervising residents and subsequently on the well-being of the direct reports.
View Article and Find Full Text PDFNavigating the COVID-19 crisis: a study of healthcare leadership response in India and the USA.
J Health Organ Manag
January 2025
Jindal Global Business School, OP Jindal Global University, Sonipat, India.
Purpose: The COVID-19 pandemic has reignited the debate on effective leadership during a crisis. The study examined healthcare leaders' experiences, challenges and responses amid the COVID-19 crisis in India and the USA.
Design/methodology/approach: Thematic analysis culminated in developing a thematic framework that encapsulates the behavior of operational healthcare leaders in India and the USA to illustrate how they responded to the global pandemic.
Development of Personas and Journey Maps for Artificial Intelligence Agents Supporting the Use of Health Big Data: Human-Centered Design Approach.
JMIR Form Res
January 2025
Big Data Convergence and Open Sharing System, Seoul National University, Seoul, Republic of Korea.
Background: The rapid proliferation of artificial intelligence (AI) requires new approaches for human-AI interfaces that are different from classic human-computer interfaces. In developing a system that is conducive to the analysis and use of health big data (HBD), reflecting the empirical characteristics of users who have performed HBD analysis is the most crucial aspect to consider. Recently, human-centered design methodology, a field of user-centered design, has been expanded and is used not only to develop types of products but also technologies and services.
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