AI Article Synopsis

  • * Conducted at Angré University Hospital between November 2019 and July 2021, the study involved 43 VAP patients out of 625 admissions, noting high mortality rates, especially in those over 50 years and on mechanical ventilation for more than 15 days.
  • * The findings highlight Klebsiella pneumoniae as a common infection cause, with a recommendation for improving treatment strategies based on identified high-risk factors.

Article Abstract

Objectives: To identify the factors of poor prognosis of ventilator-associated lung disease (VAP) in order to improve their management.

Patients And Method: Prospective, descriptive and analytical study of patients admitted to intensive care at the Angré University Hospital from November 1, 2019 to July 31, 2021 and having presented VAP.

Results: We collected 43 patients out of 625 admissions, i.e. 6.88%. The average age was 49.06 years. The sex ratio was 0.38. The main reason for admission was coma with 88.37%. Hypertension and diabetes were the main antecedents. Early VAP accounted for 53.49%. Klebsiella pneumoniae was the main germ. Patients intubated on admission accounted for 79.07%. The average duration of ventilation was 26.95 days and the average duration of hospitalization was 30.8140 days. Probabilistic antibiotic therapy was performed in 75.76% of patients. Mortality was 76.74%. The mortality factors were duration of mechanical ventilation greater than 15 days and age greater than 50 years.

Conclusion: Secondary mortality from VAP remains high. The identification of the two prognostic factors should improve the subsequent management of all new cases.

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