A silver-catalyzed cascade cyclization strategy has been developed for the synthesis of 4-aminotetrahydrocarbazole, a common core structure found in various alkaloids. This target molecule can be synthesized through a one-step tandem cyclization reaction, thereby eliminating the need for a prior synthesis of tetrahydrocarbazole. Furthermore, the use of chiral -butylsulfinamide facilitates chiral resolution of the resulting product.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d4cc03723e | DOI Listing |
Publication Analysis
Top Keywords
silver-catalyzed cascade
8
cascade cyclization
8
synthesis 4-aminotetrahydrocarbazole
8
cyclization synthesis
4
4-aminotetrahydrocarbazole silver-catalyzed
4
cyclization strategy
4
strategy developed
4
developed synthesis
4
4-aminotetrahydrocarbazole common
4
common core
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!