A rare case of extraskeletal Ewing sarcoma.

Radiol Case Rep

Baylor University Medical Center, Department of Radiology, 3500 Gaston Avenue, Dallas, Texas, 75246, USA.

Published: December 2024

AI Article Synopsis

  • Extraskeletal Ewing Sarcoma is a rare type of tumor that occurs in soft tissues, rather than bones.
  • Primary Ewing Sarcoma in the lungs is a very unusual variant, with only a few cases documented.
  • A specific case highlights a 43-year-old woman with a locally invasive lung mass that was confirmed through biopsy to be Ewing Sarcoma.

Article Abstract

Extraskeletal Ewing Sarcoma is a rare tumor of the soft tissues. Primary Ewing Sarcoma of the lung is an exceedingly uncommon variant of Extraskeletal Ewing Sarcoma, with only a small number of cases reported in the literature. We present a case of a 43-year-old woman who presented with a locally invasive mass of the right lung, biopsy-proven to be Ewing Sarcoma.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11461951PMC
http://dx.doi.org/10.1016/j.radcr.2024.09.048DOI Listing

Publication Analysis

Top Keywords

ewing sarcoma
20
extraskeletal ewing
12
ewing
5
sarcoma
5
rare case
4
case extraskeletal
4
sarcoma extraskeletal
4
sarcoma rare
4
rare tumor
4
tumor soft
4

Similar Publications

Human cancer cell lines are the mainstay of cancer research. Recent reports showed that highly mutated adult carcinoma cell lines (mainly HeLa and MCF-7) present striking diversity across laboratories and that long-term continuous culturing results in genomic/transcriptomic heterogeneity with strong phenotypical implications. Here, we hypothesize that oligomutated pediatric sarcoma cell lines mainly driven by a fusion transcription factor, such as Ewing sarcoma (EwS), are genetically and phenotypically more stable than the previously investigated adult carcinoma cell lines.

View Article and Find Full Text PDF

Ewing's sarcoma of the head and neck: differential diagnosis, treatment and outcomes.

Curr Opin Otolaryngol Head Neck Surg

December 2024

Department of Radiodiagnosis, Tata Memorial Hospital, Mumbai, HBNI, Parel, Mumbai.

Purpose Of Review: Ewing's sarcoma is a small round-cell tumour typically arising in the bones, and only rarely affecting soft tissues. These are rarely seen in the head and neck comprising 1-9% of all cases, making management of these tumours a challenge. This review aims to review the current literature to update the current diagnostic and treatment options in head and neck Ewing's sarcoma.

View Article and Find Full Text PDF

Large-scale combination drug screens are generally considered intractable due to the immense number of possible combinations. Existing approaches use ad hoc fixed experimental designs then train machine learning models to impute unobserved combinations. Here we propose BATCHIE, an orthogonal approach that conducts experiments dynamically in batches.

View Article and Find Full Text PDF

Germline structural variants are a risk factor for pediatric extracranial solid tumors.

View Article and Find Full Text PDF

Pediatric solid tumors are a leading cause of childhood disease mortality. In this work, we examined germline structural variants (SVs) as risk factors for pediatric extracranial solid tumors using germline genome sequencing of 1765 affected children, their 943 unaffected parents, and 6665 adult controls. We discovered a sex-biased association between very large (>1 megabase) germline chromosomal abnormalities and increased risk of solid tumors in male children.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!