Plasmonic sensors utilizing surface plasmon resonance (SPR) have emerged as powerful tools for sensitive and label-free detection across a wide range of applications. This study introduces a new dual-core silver-coated plasmonic sensor designed to significantly enhance sensitivity and resolution, making it particularly effective for precise analyte detection in complex environments. A key innovation of this sensor lies in its dual-core architecture, which achieves the highest wavelength sensitivity reported at 30,000 nm/RIU and resolution of RIU, covering a broad refractive index (RI) range from 1.34 to 1.41. Furthermore, the integration of machine learning (ML) algorithms, including multiple-variable linear regression (MLR), support vector regression (SVR), and random forest regression (RFR), marks a significant advancement in sensor design. These algorithms enable dynamic adaptation and the extraction of data-driven insights, enhancing the sensor's performance in predicting confinement loss and wavelength across various analytes. The innovative combination of a dual-core design and ML integration positions this plasmonic sensor as a highly sensitive and versatile tool well-suited for advanced bio-sensing applications.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11461987PMC
http://dx.doi.org/10.1016/j.heliyon.2024.e38175DOI Listing

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