As screwed joints, dental restorations may suffer mechanical failures such as screw loosening and implant or prosthetic screw failure due to fatigue. This work is focused on the failure of the implant and develops a numerical methodology to predict its fatigue life under cyclic loading conditions. This methodology is based on the combination of Critical Plane Methods and the Theory of Critical Distances to account for stress multiaxiality and notch effects. The obtained predictions were validated experimentally, which can be used to identify the main geometrical, assembly and operational factors affecting the fatigue behavior of dental implants. As a result, a powerful and efficient design tool for fatigue life prediction of dental implants is presented. This methodology complements a previously presented one focused on the fatigue life prediction of the prosthetic screw, thereby, offering now a complete design tool package regardless the critical component of the dental restoration, predicting accurately the fatigue response of the restoration, with no need for long-term fatigue test campaigns. This is a pioneering work since no other fatigue design methodology for dental implants with such a solid foundation and experimental validation has been published to date.
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http://dx.doi.org/10.1016/j.heliyon.2024.e36777 | DOI Listing |
Semin Immunopathol
January 2025
Department of Medicine II, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.
The brain-gut axis constitutes the basis for the bidirectional communication between the central nervous system and the gastrointestinal tract driven by neural, hormonal, metabolic, immunological, and microbial signals. Alterations in the gut microbiome composition as observed in inflammatory bowel diseases can modulate brain function and emerging empirical evidence has indicated that interactions among the brain-gut microbiome-axis seem to play a significant role in the pathogenesis of both inflammatory bowel diseases and psychiatric disorders and their comorbidity. Yet, the immunological and molecular mechanisms underlying the co-occurrence of inflammatory bowel diseases and psychological symptoms are still poorly understood.
View Article and Find Full Text PDFJ Adolesc Young Adult Oncol
January 2025
Deakin University, Institute for Physical Activity and Nutrition (IPAN), Geelong, Australia.
To investigate cardiorespiratory fitness (CRF), body composition, health behaviors, and health-related quality of life (HRQoL) in adolescent and young adult cancer survivors (AYA-CS) compared with age-matched counterparts without a cancer diagnosis. This cross-sectional study recruited participants aged 15-25 years at the time of their cancer diagnosis and ≥ 5 years post-treatment. Participants completed cardiopulmonary exercise testing, dual-energy X-ray absorptiometry, food diaries, physical activity (PA), fatigue, and HRQoL questionnaires.
View Article and Find Full Text PDFAim: Maternal morbidities present a major burden to the health and well-being of childbearing women. However, their impacts on women's quality of life (QoL) are not well understood. This work aims to describe the extent to which the morbidities women experience during pregnancy and postpartum affect their QoL and identify any protective or risk factors.
View Article and Find Full Text PDFCogn Neurodyn
December 2025
Faculty of Psychology, Naval Medical University (Second Military Medical University), No. 800 Xiangyin Road, Yangpu District, Shanghai, 200433 China.
Fatigue-induced incidents in transportation, aerospace, military, and other areas have been on the rise, posing a threat to human life and safety. The determination of fatigue states holds significant importance, especially through reliable and conveniently available physiological indicators. Here, a portable custom-built fNIRS system was used to monitor the fatigue state caused by nap deprivation.
View Article and Find Full Text PDFBMC Nurs
January 2025
Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia.
Background: Nursing is a caring profession for which compassion is a core value. Increasing stress and declining job satisfaction are among the major challenges in nursing. Demographic and work-related factors may influence nurses' compassion satisfaction and compassion fatigue (i.
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