AI Article Synopsis
- The review covers 30 years of research linking infections to chronic respiratory diseases like asthma, COPD, and bronchiectasis, particularly focusing on how infections contribute to these conditions.
- Recent findings show that infections increase the risk of asthma flare-ups and may lead to bronchiectasis in certain individuals.
- The article also discusses the immune system's role in chronic lung diseases, along with the challenges in diagnosing and treating these conditions while suggesting areas for future research.
Article Abstract
This review summarizes the research progress over the past 30 years on the relationship between infection and chronic respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and bronchiectasis. is a common cause of community-acquired pneumonia, particularly in children and young adults. Key findings from recent studies indicate that infection is associated with a higher risk of asthma exacerbations and may contribute to the development of bronchiectasis in susceptible individuals. Additionally, emerging evidence suggests that -induced immune dysregulation plays a crucial role in the pathogenesis of chronic lung diseases. This review aims to summarize the current understanding of the potential links between pneumonia and various chronic respiratory conditions, including asthma, chronic obstructive pulmonary disease (COPD), and bronchiectasis. We discuss the epidemiological data, pathogenic mechanisms, clinical manifestations, and long-term consequences of -related respiratory illnesses. Additionally, we highlight the challenges in diagnosis and treatment, as well as future research directions in this field.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11461384 | PMC |
| http://dx.doi.org/10.3389/fmed.2024.1437731 | DOI Listing |
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