AI Article Synopsis
- A clinical study was conducted to assess the effect of a neurocosmetic cream on reducing discomfort and enhancing recovery after radiofrequency (RF) microneedling in 11 healthy female subjects.
- Results showed that the neurocosmetic was well-tolerated and effectively reduced skin irritation, with 83% of participants agreeing it helped reduce post-procedure irritation after 24 hours.
- By the end of the study, 100% of participants reported a positive experience and a desire to return for further treatments, indicating the cream's efficacy over a leading comparator.
Article Abstract
Background: Radiofrequency (RF) microneedling produces patient discomfort which deters patients from completing the recommended treatment series.
Objective: The primary objective was to determine the tolerability, safety, and efficacy of a neurocosmetic postprocedure cream post-RF microneedling in reducing patient discomfort and enhancing recovery across the length of the study and, secondarily, to evaluate against a leading comparator. The third objective was to evaluate the efficacy of the neurocosmetic on self-perceived improvement and objective grading.
Materials And Methods: An Institutional Review Board (IRB) approved, fourteen-day, randomized, single-center, double-blind, controlled clinical case study was conducted with 11 healthy female subjects, 6 randomized to the neurocosmetic and 5 to the comparator cell. Following a 7-day washout period, subjects received RF microneedling (face and neck) and applied the postprocedure cream twice daily for 7 days. Objective and subjective tolerability, self-assessments, and clinical photography were performed immediately postprocedure, 24 h, three and seven days following the procedure.
Results: The neurocosmetic was tolerable and safe. Erythema and stinging immediately decreased postprocedure, postneurocosmetic application. After 24 h, 83% favorably agreed the neurocosmetic "reduced irritation on the skin post-procedure," and after 7 days, 100% favorably agreed "experience with the product was positive and I would be interested in returning for a second treatment." The neurocosmetic reduced skin tone redness in the face and neck faster and to a greater degree when measured against a comparator.
Conclusion: The neurocosmetic postprocedure cream improved patient discomfort and enhanced recovery when used immediately post-RF microneedling and after 7 days.
Irb Protocol Number: Pro00064211.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626329 | PMC |
| http://dx.doi.org/10.1111/jocd.16622 | DOI Listing |
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