The 2023 Cure Ocular Melanoma (CURE OM) Global Science Meeting was held in Philadelphia on November 6, 2023. There is increased awareness and dedicated research in uveal melanoma (UM), but unmet needs remain in the prevention, detection, and treatment of UM. The purpose of this meeting was to provide an international forum for the exchange of research ideas, to allow for discussion of basic science as well as clinical research on UM, and to gather input about advocacy and patient needs.
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Prevalence of Schistosoma infection and associated factors among pregnant women attending antenatal care at Shewa Robit Health Center, North-Central Ethiopia: a cross-sectional study.
Trop Med Health
December 2024
Department of Medical Laboratory Science, College of Medicine and Health Sciences, Bahir Dar University, P.O. Box 79, Bahir Dar, Ethiopia.
Background: Schistosoma spp. and other intestinal parasites are common in Ethiopia. During pregnancy, SCH increases the risk of adverse birth outcomes.
View Article and Find Full Text PDFComparison of glucocorticoids combined with antiviral drugs versus glucocorticoids alone in the management of Bell's Palsy: A systematic review and meta-analysis of randomized clinical trials.
Am J Otolaryngol
December 2024
Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, No. 20 East Yuhuangding Road, Yantai 264000, Shandong, PR China; Shandong Provincial Key Laboratory of Neuroimmune Interaction and Regulation, PR China; Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai 264000, Shandong, PR China; Yantai Key Laboratory of Otorhinolaryngologic Diseases, Shandong, PR China. Electronic address:
Objective: This study aimed to compare the efficacy of glucocorticoids combined with antiviral drugs (GA) versus glucocorticoids alone (GO) in the treatment of Bell's Palsy.
Database Reviewed: According to the PRISMA2020 guidelines, we searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials for English articles from their inception to August 10, 2023, and performed a secondary search on October 31, 2024.
Methods: Studies describing the efficacy of (GA) for Bell's Palsy versus (GO).
Immune Checkpoint Inhibitors in Patients with Testicular Cancer: A Systematic Review.
J Adolesc Young Adult Oncol
December 2024
Facultad de Medicina, Centro de Desarrollo de Investigación 360, Universidad Autónoma de Nuevo León, Monterrey, Mexico.
Germ cell tumors (GCTs) are chemosensitive neoplasms with high cure rates; however, a small group of patients present tumors with refractory chemotherapy, with a dismal prognosis and few effective management options. Although immune checkpoint inhibitors (ICIs) are approved for use in chemotherapy refractory GCT, the evidence supporting this indication remains scarce. Original research studies were included on patients with GCTs refractory to chemotherapy treated with ICI up to December 2023.
View Article and Find Full Text PDFIntroduction: Rabies continues to be a significant concern in India, with lots of deaths reported annually. Approximately one million people undergo post-exposure prophylaxis treatment annually, despite nearly two million dog bites occurring across the country. Notably, dogs are responsible for more than 99% of these bites.
View Article and Find Full Text PDFCombination of spatial transcriptomics analysis and retrospective study reveals liver infection of SARS-COV-2 is associated with clinical outcomes of COVID-19.
EBioMedicine
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Liver Cancer Institute, Zhongshan Hospital, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Fudan University, Shanghai, China. Electronic address:
Background: Liver involvement is a common complication of coronavirus disease 2019 (COVID-19), especially in hospitalized patients. However, the underlying mechanisms involved are not fully understood.
Methods: Immunohistochemistry (IHC) staining of SARS-CoV-2 spike (S) and nucleocapsid (N) proteins was conducted on liver tissues from six patients with COVID-19.
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