AI Article Synopsis

  • A 54-year-old man experienced left lower quadrant pain, and while a CT scan found no clear cause, it revealed a 2.0-cm lesion in his pancreatic tail.
  • EUS-guided biopsy showed only benign tissue, leading to a 64 Cu-DOTATATE PET/CT scan that indicated the presence of a well-differentiated neuroendocrine tumor.
  • However, surgery revealed focal chronic pancreatitis with islet aggregation, which mimicked a neuroendocrine tumor on the PET/CT scan.

Article Abstract

A 54-year-old man presented with left lower quadrant pain. CT showed no cause for his pain but identified an incidental 2.0-cm enhancing lesion in the pancreatic tail. On MRI, this lesion was hyperenhancing and diffusion-restricting, suspicious for a neuroendocrine tumor. However, EUS-guided biopsy yielded only benign pancreatic tissue. Due to this discordance, 64 Cu-DOTATATE PET/CT was performed. The pancreatic tail lesion was tracer-avid, suggesting a well-differentiated neuroendocrine tumor. Based on the PET findings, the patient underwent distal pancreatectomy. Surgical pathology revealed only focal chronic pancreatitis with islet aggregation, a previously undescribed mimic of neuroendocrine tumor on DOTATATE PET/CT.

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Source
http://dx.doi.org/10.1097/RLU.0000000000005516DOI Listing

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