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Pharmacological and non-pharmacological therapies for prevention and treatment of osteoporosis in Duchenne Muscular Dystrophy: A systematic review.
Bone
January 2025
Department of Paediatric Endocrinology, Royal Hospital for Children, Glasgow, United Kingdom; School of Medicine, Dentistry & Nursing, University of Glasgow, United Kingdom. Electronic address:
Background: Long term glucocorticoid treatment in Duchenne Muscular Dystrophy (DMD) is associated with a high incidence of fragility fractures. This systematic review aims to assess the current evidence for pharmacological and non-pharmacological treatment for osteoporosis in children and adults with DMD.
Methods: Three online databases (Embase, Medline, Cochrane Library) were searched for studies that evaluated interventions for treatment or prevention of osteoporosis in DMD.
Addressing unmet mental health needs of older adults in Turbo, Colombia: a multi-component psychosocial intervention feasibility study.
Int J Equity Health
January 2025
National School of Public Health, University of Antioquia, Medellín, Colombia.
Background: Older adults have lived through extreme and stressful live events in Colombia, including during the armed conflict. Without adequate mental health resources in place, the aim of this study was to feasibility test a co-produced community-integrated intervention for older adults to improve their mental health and well-being in Turbo, Colombia.
Methods: Based on a systematic review and meta-analysis of community-based mental health interventions for older adults in LMICs, qualitative interviews with older adults and local stakeholders, as well as a mental health needs assessment survey of the local older adult population in Turbo, Colombia, we consulted older adults in the region to co-produce a community-based intervention.
Association between interhospital transfer status and outcomes following nontraumatic subdural hemorrhage.
J Clin Neurosci
January 2025
Ochsner Medical Center, Department of Neurosurgery, Jefferson, LA, United States.
Background: Patients with nontraumatic subdural hemorrhage often require immediate surgical intervention that may not be available at community hospitals and are therefore transferred to tertiary care centers. This study aims to evaluate the effects of interhospital transfer (IHT) on postoperative complications and outcomes following ntSDH.
Methods: The National Surgical Quality Improvement Program (NSQIP) database was queried for patients treated for ntSDH from January 2014 to January 2020.
A two-tier optimization strategy for feature selection in robust adversarial attack mitigation on internet of things network security.
Sci Rep
January 2025
Computer Science Department, Faculty of Computers and Information, South Valley University, Qena, 83523, Egypt.
Adversarial attacks were commonly considered in computer vision (CV), but their effect on network security apps rests in the field of open investigation. As IoT, AI, and 5G endure to unite and understand the potential of Industry 4.0, security events and incidents on IoT systems have been enlarged.
View Article and Find Full Text PDFA comprehensive study of quantum arithmetic circuits.
Philos Trans A Math Phys Eng Sci
January 2025
College of Computing and Data Science, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore.
In recent decades, the field of quantum computing has experienced remarkable progress. This progress is marked by the superior performance of many quantum algorithms compared with their classical counterparts, with Shor's algorithm serving as a prominent illustration. Quantum arithmetic circuits, which are the fundamental building blocks in numerous quantum algorithms, have attracted much attention.
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