Background: The aim of this study is to investigate the impact of sex on the clinical outcomes of spousal donor kidney transplantation.
Methods: We analyzed 456 spousal donor kidney transplantation recipients and categorized them into standard or high immunological risk groups according to panel-reactive antibody ≥50% or less. There were 366 recipients in the standard-risk group and 89 recipients in the high-risk group.
Results: When comparing biopsy-proven allograft rejection within 1 year from kidney transplantation, husband-to-wife recipients showed significantly higher incidence than wife-to-husband recipients in the high-risk group. By contrast, there was no significant difference between wife-to-husband and husband-to-wife recipients in the standard-risk group. Allograft function recovery was better in husband-to-wife recipients than in wife-to-husband recipients in each group, while husband-to-wife recipients in the high-risk group showed a more rapid decline than other recipients. The long-term patient and allograft survival rates showed no difference between husband-to-wife recipients and wife-to-husband recipients within the same groups.
Conclusion: The husband-to-wife recipients with high immunological risk showed a higher risk of biopsy-proven allograft rejection compared to wife-to-husband recipients, so careful monitoring and management may be required.
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Impact of sex on clinical outcomes according to immunologic risk in spousal donor kidney transplantation.
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Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Background: The aim of this study is to investigate the impact of sex on the clinical outcomes of spousal donor kidney transplantation.
Methods: We analyzed 456 spousal donor kidney transplantation recipients and categorized them into standard or high immunological risk groups according to panel-reactive antibody ≥50% or less. There were 366 recipients in the standard-risk group and 89 recipients in the high-risk group.
[Husband to wife renal transplantatation and pretransplant HLA immunization: about two cases].
Pan Afr Med J
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Service d'Immunologie et de Transfusion, Centre Hospitalier Universitaire Ibn Sina de Rabat, Rabat, Maroc.
Renal transplantation is the best therapeutic approach for end-stage kidney disease. Renal transplantation can be performed using living donors or brain-dead donors. Vaccination in recipients poses a real problem with the transplantation process because it is responsible for particular difficulties in choosing a donor and above all exposes to the risk of transplant rejection.
View Article and Find Full Text PDFOutcomes of Living-Donor Kidney Transplantation in Female Recipients with Possible Pregnancy-Related Pre-Sensitization According to Donor Relationship.
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Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
BACKGROUND Given that pregnancy is an immune-sensitizing event, female kidney transplant recipients who receive allografts from their offspring or husbands may have a higher risk of rejection and graft failure due to pre-sensitization acquired during pregnancy or childbirth. We investigated the association between donor relatedness (i.e.
View Article and Find Full Text PDFGender Disparity and the Relationship Between Living Donors and Recipients in Kidney Transplants in an Organ Transplant Center in Turkey.
Exp Clin Transplant
January 2019
From The Department of Public Health, Baskent University, Ankara, Turkey.
Objectives: The literature search on kidney transplant procedures performed in Turkey showed that few publications are available about gender distribution and the relationships between living donors and recipients. Therefore, this study aimed to examine the gender distributions and the relationships between donors and recipients of living-donor kidney transplants performed in a university hospital in Ankara, Turkey.
Materials And Methods: In this study, we retrospectively analyzed the hospital records of living kidney donors (1611 cases) and all 1991 kidney recipients who underwent living-donor and deceased-donor kidney transplant procedures in a university hospital between 1985 and 2017.
Gender Imbalance and the Relationship Between Living Donors and Recipients in Liver Transplantations in an Organ Transplant Center in Turkey.
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January 2019
From the Department of Public Health, Baskent University, Ankara, Turkey.
Objectives: Because of the scarcity of publications on gender differences and the relationship between living donors and recipients in liver transplant procedures, we carried out this study with the objective to examine the gender distribution of donors and recipients and the relationships between donors and recipients in living related-donor liver transplants performed in a university hospital in Ankara, Turkey.
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