AI Article Synopsis
- Ridge preservation is important for maintaining alveolar ridge volume and improving dental implant outcomes, and this study investigates the effect of adding hyaluronic acid to allografts used for this purpose.
- In a study of 40 patients, those receiving allogeneic bone substitutes with hyaluronic acid experienced significantly less vertical height loss and graft shrinkage compared to those who received allografts without it.
- The findings indicate that adding hyaluronic acid to allografts leads to better graft stability and increased bone density, enhancing the success of ridge preservation after tooth extraction.
Article Abstract
Purpose: Ridge preservation is essential to restore alveolar ridge volume and to enhance esthetic and functional outcomes for dental implants. The addition of hyaluronic acid to allogeneic bone substitute materials might enhance these outcomes. This clinical study evaluated the efficacy of ridge preservation after tooth extraction using granular allografts with and without hyaluronic acid addition.
Methods: In this retrospective study, 40 patients with compromised extraction sockets were enrolled. Among them, 19 received particulate allogeneic bone substitutes (Allo), 21 received allogeneic bone substitutes with hyaluronic acid (AlloHya). Vertical and horizontal graft stability, graft shrinkage rate, and bone mineral density were assessed using radiographic measurements on CBCT scans conducted before tooth extraction, directly after ridge preservation and after four months. Patients were followed up 12 months post-implantation.
Results: Vertical height loss after 4 months was significantly greater in the Allo group (-0.82 ± 0.95 mm) compared to the AlloHya group (-0.19 ± 0.51 mm; p = 0.011). Graft shrinkage rate was 16.9 ± 11.5% (Allo) and 10.3 ± 7.7% (AlloHya) (p = 0.038). After four months, average bone density was significantly higher in the AlloHya compared to the Allo group (p = 0.004). Nearly all implants (39 out of 40) were classified as "Success" according to the ICOI scheme, with no differences in implant quality between the two study groups.
Conclusions: Improved graft stability, reduced resorption, and increased bone density were observed in hyaluronic acid-enriched allografts compared to pure allografts. Adding hyaluronic acid to allogeneic bone grafts significantly enhanced outcomes in ridge preservation.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11465134 | PMC |
| http://dx.doi.org/10.1186/s40729-024-00559-6 | DOI Listing |
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