Clinical performance evaluation of the BioFire Joint Infection Panel.

J Clin Microbiol

Microbiology Service, Department of Laboratory Medicine, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.

Published: November 2024

AI Article Synopsis

  • The BioFire Joint Infection (JI) Panel improves the diagnosis of joint infections by quickly detecting multiple bacteria and fungi, as well as resistance markers, from synovial fluid samples.
  • An article by Moran et al. discusses real-world uses of the panel, showcasing its effectiveness and efficiency in clinical settings.
  • While the panel has advantages like quick results and identifying tough pathogens, it also has limitations, especially in detecting some organisms not included in the test.

Article Abstract

The BioFire Joint Infection (JI) Panel offers a significant advancement in the rapid diagnosis of joint infections by facilitating the simultaneous detection of multiple bacterial and fungal pathogens, as well as resistance markers, directly from synovial fluid samples. An article published in the by Moran et al. (J Clin Microbiol 62:e00182-24, 2024, https://doi.org/10.1128/jcm.00182-24) presents both prospective and retrospective analyses of the panel's real-world clinical application. The study highlights the panel's benefits, such as its rapid turnaround time and ability to identify challenging pathogens, while also discussing its limitations, particularly in detecting certain off-panel organisms.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559011PMC
http://dx.doi.org/10.1128/jcm.01022-24DOI Listing

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