AI Article Synopsis
- *Many of these nanomedicines perform better in animal studies than in actual therapeutic outcomes, raising concerns about their efficacy.
- *The review discusses the challenges in the field, such as issues with the enhanced permeability and retention effect, production methods, and highlights new opportunities from advancements in artificial intelligence.
Article Abstract
Poly(amino acid) nanomedicines hold significant promise for cancer therapy. However, their clinical translation has not matched the extensive efforts of scientists or the burgeoning body of research. The therapeutic outcomes with most nanomedicines often fall short of the promising results observed in animal experiments. This review explores the challenges faced in cancer therapy using poly(amino acid) nanomedicines, particularly addressing the controversies surrounding the enhanced permeability and retention effect and the lack of methods for controlled and reproducible mass production of poly(amino acid) nanomedicines. Furthermore, this review examines the opportunities emerging in this field due to the rapid advancements in artificial intelligence.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520535 | PMC |
| http://dx.doi.org/10.1080/17435889.2024.2402677 | DOI Listing |
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