AI Article Synopsis
- Childhood cancers affect about 1 in 500 kids, but each specific type is pretty rare.
- Research is not just about finding cures; it's also about helping kids deal with treatment side effects like infections and nausea.
- To make things better, doctors need to work together and find new ways to help kids as treatments improve and change.
Article Abstract
Introduction: Childhood cancers as a group affect around 1 in 500 children but each individual diagnosis is a rare disease. While research largely focuses on improving cure rates, the management of side effects of treatment are high priority for clinicians, families and children and young people.
Areas Covered: The prevention and efficient management of infectious complications, oral mucositis, nausea and vomiting and graft-vs-host disease illustrated with examples of implementation research, translation of engineering to care, advances in statistical methodologies, and traditional bench-to-patient development. The reviews draw from existing systematic reviews and well conducted clinical practice guidelines.
Expert Opinion: The four areas are driven from patient and family priorities. Some of the problems outlined are ready for proven interventions, others require us to develop new technologies. Advancement needs us to make the best use of new methods of applied health research and clinical trial methodologies. Some of the greatest challenges may be those we're not fully aware of, as new therapies move from their use in adult oncological practice into children. This will need us to continue our collaborative, multi-professional, multi-disciplinary and eclectic approach.
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| http://dx.doi.org/10.1080/14737140.2024.2411255 | DOI Listing |
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