Objective: Minor salivary gland carcinomas are challenging to study due to their rarity and heterogeneity. We aim to further characterize clinical characteristics, treatment, and outcomes over 20 years within a single institution.

Study Design: Retrospective chart review was conducted on 210 patients who received primary treatment for minor salivary gland malignancy from 2000 to 2022.

Setting: Single tertiary-care center.

Methods: Multivariable Cox proportional hazards method was used to examine the relationship between pre-determined clinically important variables and outcomes.

Results: Five-year overall survival was 77.8% (72.0-84.1). Advanced clinical T stage portended over a 2 times higher risk of death and recurrence. High pathologic grade was associated with a near 3 times higher risk of death and recurrence. There was a predominance of occult nodal metastases in level II for oral cavity and oropharynx site tumors.

Conclusion: Clinical T stage and grade were important for overall survival, local, regional, and distant recurrence-free survival. Occult nodal metastases occurred most often in level II.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11459202PMC
http://dx.doi.org/10.1002/oto2.70030DOI Listing

Publication Analysis

Top Keywords

minor salivary
12
salivary gland
12
clinical stage
8
times higher
8
higher risk
8
risk death
8
death recurrence
8
occult nodal
8
nodal metastases
8
outcomes minor
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!