AI Article Synopsis
- Rope bamboo has medicinal properties, with its extracts showing antioxidant and anti-inflammatory effects, and this study explores its liquid smoke's role in wound healing in mice.
- The study used liquid chromatography-mass spectrometry to identify compounds in the liquid smoke and conducted experiments over 14 days to measure wound healing using different concentrations (100%, 50%, 25%).
- Results indicated that the 100% concentration significantly accelerated healing compared to lower concentrations, suggesting that the beneficial effects are linked to the bioactive compounds in Rope bamboo's liquid smoke, acting in a dose-dependent manner.
Article Abstract
Purpose: Rope bamboo () is traditionally used for medicinal purposes, and extracts from stem leaves and shoots have been shown to possess antioxidant and anti-inflammatory activity. Thus, this study looked at the potential compounds present in and the usefulness of Rope bamboo liquid smoke preparations in the wound healing process in mice.
Methods: The fingerprinting of the liquid smoke was done by liquid chromatography-mass spectrometry. In-vivo experiments were conducted to observe the diameter and percentage of wound healing in mice for 14 days using topical formulations containing liquid smoke concentrations of 100%, 50%, 25%, positive control and negative control. Statistical analyses were conducted using the Kruskal-Wallis test and Spearman correlation.
Results: The phytochemical fingerprint showed the presence of alkaloids, flavonoids, vitamins, phenols, and lipids. The 100% undiluted liquid smoke accelerated wound healing faster compared to 50% and 25% dilutions. The differences in wound diameters were statistically significant across treatments having a of 0.020 and dose-dependent ().
Conclusion: Liquid smoke acceleration of the wound healing process was dose-dependent compared to controls. This dose-dependency indicates that the wound healing effects were probably due to the anti-inflammatory, antioxidant, and antimicrobial activities of the elucidated constituents of Rope bamboo liquid smoke.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460353 | PMC |
| http://dx.doi.org/10.2147/JEP.S479862 | DOI Listing |
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