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Biofilm inhibition and antimicrobial activity of a dentifrice containing salivary substitutes.
Int J Dent Hyg
November 2007
Department of Periodontics, SDM College of Dental Sciences and Hospital, Sattur, Dharwad, Karnataka, India.
Background/aims: A healthy mouth harbours the continuous combined action of a salivary defence system with that of a salivary peroxidase system, containing lactoferrin, lysozyme, immunoglobulin and growth factors. This system maintains neutral pH and creates an oral environment where harmful bacteria are inhibited, thus preventing the formation of biofilms. The objective of this clinico-microbiological trial was to evaluate the anti-plaque effect of a dentifrice containing salivary substitutes, compared with a placebo-control dentifrice and to assess the effect of dentifrice on oral bacterial count.
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