Unusual pattern: Diffuse pulmonary FDG uptake on PET/CT.

Radiol Case Rep

Department of Radiology, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA.

Published: December 2024

AI Article Synopsis

  • - A 75-year-old female with lung metastasis from head and neck squamous cell carcinoma exhibited a mass in the right lung area, alongside unusual 18-FDG uptake, without visible lung abnormalities on a CT scan.
  • - Initial thoughts leaned towards lymphangitic spread of the cancer, indicating spread through lymphatic vessels.
  • - However, follow-up imaging revealed a mass invading the right inferior pulmonary vein and significant decreased blood flow in specific lung lobes, leading to a diagnosis of right pulmonary venous occlusion instead.

Article Abstract

A 75-year-old nonsmoker and nonalcoholic female, known to have squamous cell carcinoma of the head and neck metastasized to the lungs, was found to have a mass at the right hilar/infra-hilar region and an unusual pattern of increased mild diffuse 18-fluorodeoxyglucose (18-FDG) uptake at the right mid-lower lobe location without any lung parenchymal abnormalities (confirmed by low dose CT scan of PET-CT). It was suspected to be the lymphangitic spread of the neoplasm; however, spectral detector CT (SDCT) imaging performed later not only confirmed the presence of a mass invading the right inferior pulmonary vein but showed a large area of significantly decreased perfusion in the right middle and lower lung lobes, leading to a change in the diagnosis to right pulmonary venous occlusion.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11459453PMC
http://dx.doi.org/10.1016/j.radcr.2024.09.069DOI Listing

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