A robust collagen-targeting MRI peptide contrast agent for imaging of hepatic fibrosis.

Chem Commun (Camb)

State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China.

Published: October 2024

AI Article Synopsis

  • Researchers developed a new MRI peptide contrast agent called Gd-ICTP.
  • This agent is highly selective for type I collagen, which is important for detecting liver fibrosis.
  • Gd-ICTP allows for accurate and non-invasive imaging, improving the diagnosis of hepatic fibrosis.

Article Abstract

We herein report the construction of a robust MRI peptide contrast agent Gd-ICTP with superior selectivity for type I collagen, enabling the accurate and non-invasive detection of hepatic fibrosis .

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Source
http://dx.doi.org/10.1039/d4cc00702fDOI Listing

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