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If antibiotics aren't always the answer-what is?
Pediatr Res
October 2024
SAPPHIRE Group, Population Health Sciences, Leicester University, Leicester, UK.
Association between the presence of CRISPR-Cas system genes and antibiotic resistance in Klebsiella pneumoniae isolated from patients admitted in Ahvaz teaching hospitals.
BMC Infect Dis
October 2024
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Background: This study aims to investigate the frequency of cas1 and cas3 and CRISPR1,2,3 genes in Klebsiella pneumoniae isolates, as well as their connection with antibiotic resistance.
Materials And Methods: 106 K. pneumoniae isolates were identified by biochemical assays and PCR.
POEMS syndrome with undetectable M-protein: a case report and literature review.
Diagn Pathol
June 2024
Department of Hematology, The First Hospital of Shanxi Medical University, 85 Jiefang South Road, Yingze District, Taiyuan, Shanxi, People's Republic of China.
Article Synopsis
- POEMS syndrome is a rare disease that affects nerves and organs, and usually needs certain signs to be diagnosed, like nerve problems and a specific type of protein.
- A 54-year-old man had various health problems including weakness in his legs and unusual skin growths, but tests didn’t show the expected protein usually linked to this syndrome.
- Even without the usual protein, doctors figured out he had a version of POEMS syndrome and he got better after treatment, showing that not having the protein doesn’t mean it can't be diagnosed.
Preclinical Data Extrapolation to Clinical Reality: A Translational Approach.
Curr Drug Discov Technol
April 2024
Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad-244001, Uttar Pradesh, India.
In vivo investigations are much more complex than trials conducted in a test tube; the results sometimes aren't as illuminating and could raise more questions than answers. Preclinical data projection into clinical truth is a transcriptional science that remains a compelling trial in drug development. Preclinical in vivo and in vitro education is important in novel drug's non-violent or active growth.
View Article and Find Full Text PDFPlatelet-Rich Fibrin for Topical Antibiotic Delivery After Sternotomy: Why Aren't We Using It?
Ann Thorac Surg
December 2023
Department of Cardiac Surgery, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
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