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Evaluation of long axial field-of-view (LAFOV) PET/CT for post-treatment dosimetry in Yttrium-90 radioembolization of liver tumors: a comparative study with conventional SPECT imaging.
Eur J Nucl Med Mol Imaging
December 2024
Department of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 18, Bern, 3010, Switzerland.
Purpose: Long axial field-of-view (LAFOV) positron emission tomography/computed tomography (PET/CT) scanners enable high sensitivity and wide anatomical coverage. Therefore, they seem ideal to perform post-selective internal radiation therapy (SIRT) Y scans, which are needed, to confirm that the dose is delivered to the tumors and that healthy organs are spared. However, it is unclear to what extent the use of LAFOV PET is feasible and which dosimetry approaches results in accurate measurements.
View Article and Find Full Text PDFBehavioral and social predictors of COVID-19 vaccine uptake among persons with disabilities in Kenya.
Front Public Health
December 2024
Department of Population Health and Environment, Amref Health Africa, Nairobi, Kenya.
Access and uptake of COVID-19 vaccine by persons with disabilities remains largely unknown in low-and middle-income countries, despite the unique barriers they face, their special vulnerabilities and higher risk to severe outcomes. We aimed to identify behavioral and social predictors of COVID-19 uptake among persons with disability in Kenya. A convergent parallel mixed method study design was conducted among 792 persons with disability in four regions (counties) in Kenya.
View Article and Find Full Text PDFDeciphering TGF-β1's Role in Drug Resistance and Leveraging Plant Bioactives for Cancer Therapy.
Eur J Pharmacol
December 2024
School of Health Sciences and Technology, UPES, Dehradun, Uttarakhand, 248007, India. Electronic address:
The intricate regulatory mechanisms governing TGF-β1 expression play pivotal roles in tumor progression. Key proteins such as FKBP1A, SMAD6, and SMAD7 trigger this process, modulating cell growth inhibition via p15INK4b and p21CIP1 induction. Despite TGF-β's tumor-suppressive functions, cancer cells adeptly evade its effects, fueling disease advancement.
View Article and Find Full Text PDFThe common prosperity effect of rural households' financial participation: a perspective based on multidimensional relative poverty.
Front Public Health
December 2024
Institute of Agricultural Economics and Development, Chinese Academy of Agricultural Sciences, Beijing, China.
Introduction: Common prosperity holds significant importance in ensuring social equity, promoting sustainable economic growth, and achieving long-term national security. The management of multidimensional relative poverty is a crucial pathway to realizing the common prosperity of all individuals. It is worthwhile to investigate whether the formal and informal financial involvement of rural households can synergistically alleviate multidimensional relative poverty, ultimately contributing to the realization of common prosperity.
View Article and Find Full Text PDF"Do good and talk about it": informal representation and migrant-led civil society organizations' mediation between low-wage labor migrants and state institutions in the GCC countries.
Comp Migr Stud
December 2024
Department of Political Science, Nieuwe Achtergracht 166, Amsterdam, 1018 WV The Netherlands.
Low-wage labor migrants experience major human and working rights abuses in the Gulf Cooperation Council countries despite national labor laws and signatures to various human rights conventions. On paper, India has established an institutional framework of transnational social protection for its officially estimated 5.5 million low-wage workers migrating to the Gulf Cooperation Council countries, e.
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