AI Article Synopsis
- - The study evaluates the effectiveness of cadaveric skin grafts followed by autologous split-thickness skin grafts (STSG) in treating various wound types over a five-year period at a Buenos Aires hospital.
- - Out of 25 patients analyzed, the cadaveric grafts showed a 96.6% success rate in engrafting, and the STSGs had a 90.6% success rate, with most patients experiencing significant improvements in pain and wound condition.
- - The findings suggest that this two-step grafting process is a safe and effective option for managing complex wounds, especially in patients with other health issues, reducing the risk of complications and improving overall outcomes.
Article Abstract
Background: Cadaveric skin grafts were initially used for the management of acute burn wounds. The biological coverage of the wound improves the quality of the wound bed, which prepares it to receive an autologous skin graft. The benefits of cadaveric skin graft in burn wounds have led to its use in the management of acute and chronic wounds of diverse etiologies.
Objective: To evaluate the use of cadaveric skin graft and subsequent autologous split-thickness skin graft (STSG) in the management of wounds of diverse etiologies at a single institution.
Materials And Methods: A retrospective analysis was performed of patients with wounds of different etiologies managed with cadaveric skin grafts followed by a second procedure in which autologous STSG was performed from May 2017 through May 2022 in the Plastic and Reconstructive Surgery Department of German Hospital, Buenos Aires, Argentina.
Results: A total of 25 patients with wounds of different etiologies were included. The mean affected body surface area (BSA) was 1.87%. The mean engraftment percentage of the cadaveric skin graft was 96.6%. The mean engraftment percentage of the STSG was 90.6%. All patients demonstrated improvement in local edema and inflammation, reduced secretions, and reduced pain after treatment. Two patients (8%) had complications, with 1 case of delayed healing of the donor site and 1 case of hypertrophic scarring.
Conclusions: Cadaveric skin graft with subsequent STSG is a simple, safe, and effective alternative for the management of complex wounds of diverse etiologies. This technique is particularly useful in patients with multiple comorbidities who are at risk of recurrence and of developing multiple wounds during their lifetime.
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| http://dx.doi.org/10.25270/wnds/24004 | DOI Listing |
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