AI Article Synopsis
- Scientists studied COVID-19 cases using data to compare vaccinated people who never had the virus to unvaccinated people who had it before.
- They found that the rate of getting a new infection was nearly the same for both groups.
- However, people who got reinfected (unvaccinated) were much more likely to end up in the hospital or die compared to those who had a breakthrough infection after being vaccinated.
Article Abstract
Using the VA COVID-19 National Database, we created matched pairs of previously uninfected vaccinated (≥2 doses of an mRNA vaccine) and previously infected unvaccinated individuals. The incidence rate (per 1000 person-days) of breakthrough infection among vaccinated individuals (0.30, 95% CI 0.29-0.32) was similar to reinfection rate among unvaccinated individuals (0.31, 95% CI 0.30-0.32; p=0.5). The incidence rate of hospitalization/death was higher after reinfection (7.31, 95% CI 6.66-8.03) compared with rate after breakthrough infection (4.69, 95% CI 4.06-5.42; P<0.0001). Conclusion: The incidence of hospitalization/death is significantly higher after reinfection among unvaccinated individuals compared with breakthrough infection after vaccination.
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| http://dx.doi.org/10.1093/infdis/jiae484 | DOI Listing |
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