AI Article Synopsis

  • - Chorioangiomas are benign tumors originating from chorionic tissue, found in about 1% of all examined placentas, and are mostly small and asymptomatic, often going unnoticed during ultrasounds.
  • - Larger chorioangiomas (over 4-5 cm) can be detected through ultrasound and are linked to potential complications for both the mother and fetus, such as preeclampsia and fetal growth issues.
  • - The study analyzes 30 cases of placental chorioangiomas, focusing on their clinical and pathological characteristics and exploring the possible molecular mechanisms behind their occurrence.

Article Abstract

Chorioangiomas are benign angiomas arising from chorionic tissue and they are the most common non-trophoblastic tumors of the placenta, as they are observed in 1% of all placentas examined. Most chorioangiomas are small and asymptomatic, often undetected during a prenatal ultrasound, and their clinical significance is still unknown. Large chorioangiomas, measuring more than 4-5 cm in diameter, can usually be detected prenatally by gray-scale or color Doppler sonography, and may be associated with maternal or fetal complications, such as preeclampsia, maternal mirror syndrome, preterm delivery, nonimmune fetal hydrops, fetal growth restriction and fetal demise. We herein describe the clinical-pathological features of a monocentric series of 30 placental chorioangiomas and discuss their clinical-pathological features and possible molecular mechanisms underlying their development.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460147PMC
http://dx.doi.org/10.32074/1591-951X-1003DOI Listing

Publication Analysis

Top Keywords

clinical-pathological features
8
chorioangiomas
5
case series
4
series chorioangiomas
4
chorioangiomas placentas
4
placentas clinical
4
clinical indication
4
indication histological
4
histological examination
4
examination chorioangiomas
4

Similar Publications

Background: Hepatic sarcomatoid carcinoma (HSC) and hepatic sarcoma (HS) are rare malignancies. Without pathology, the differential diagnosis between these two tumors is difficult due to their frequent overlaps in clinical presentations and imaging features. Currently, there are limited analyses about the ultrasound (US), contrast-enhanced ultrasound (CEUS) and contrast-enhanced computer tomography (CECT) characteristics of HSC and HS.

View Article and Find Full Text PDF

Background: Patients with gastric cancer (GC) who experience early recurrence (ER) within 2 years postoperatively have poor prognoses. This study aimed to analyze and predict ER after curative surgery for patients with GC using machine learning (ML) methods.

Patients And Methods: This multicenter population-based cohort study included data from ten large tertiary regional medical centers in China.

View Article and Find Full Text PDF

Background/aim: Sarcoidosis is a multisystem disorder that affects many organs, including the kidneys. This single-center retrospective study investigated the clinical, pathological, and laboratory findings of patients with kidney sarcoidosis who were treated with immunosuppressives.

Materials And Methods: Twenty-three patients with biopsy-confirmed kidney sarcoidosis were included.

View Article and Find Full Text PDF

Correlation between ultrasonography and elastography parameters and molecular subtypes of breast cancer in young women.

Ann Med

December 2025

Department of Ultrasonographl, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi Province, China.

Objective: To explore the differences of conventional ultrasound characteristics, elastic imaging parameters and clinicopathological characteristics of distinct molecular subtypes of breast cancer in young women, and to identify imaging parameters that exhibited significant associations with each molecular subtype.

Methods: We performed a retrospective analysis encompassing 310 young women with breast cancer. Observations were made regarding the ultrasonography and elastography characteristics of the identified breast lesions.

View Article and Find Full Text PDF

Lung adenocarcinoma (LUAD) represents one of the most common subtypes of lung cancer with high rates of incidence and mortality, which contributes to substantial health and economic demand across the globe. Treatment today mainly consists of surgery, radiotherapy, and chemotherapy, but their efficacy in advanced stages is often suboptimal and emphasizes the clear need for new biomarkers and therapeutic targets. Using comprehensive bioinformatics analyses consisting of the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), Human Protein Atlas (HPA) and Clinical Proteomic Tumor Analysis Consortium (CPTAC), immune infiltration analysis and functional enrichment analysis, and single-cell analysis, we examined the potential of keratin 18 (KRT18) as a candidate biomarker in advanced LUAD.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!