AI Article Synopsis
- * It has shown potential benefits in improving mitochondrial function, reducing inflammation, and helping with complications like kidney disease and retinopathy in diabetic patients.
- * However, its effectiveness is limited by poor absorption, and this review explores ways to enhance its delivery, suggesting it could be a beneficial addition to diabetes treatment strategies if these challenges are addressed.
Article Abstract
Coenzyme Q has garnered significant attention due to its potential role in enhancing cellular energy production and its antioxidant properties. We delve into the therapeutic potential of coenzyme Q in managing diabetes mellitus and its complications, highlighting its capacity to improve mitochondrial function, reduce inflammation and oxidative stress, and correct lipid profiles. Coenzyme Q has shown promise in ameliorating insulin resistance and alleviating complications such as diabetic peripheral neuropathy, kidney disease, retinopathy, and cardiomyopathy. However, its clinical application is limited by poor bio-availability. This review also provides a comprehensive overview of current therapeutic strategies for diabetes complications involving coenzyme Q, including stimulating endogenous synthesis and utilizing carrier transport systems, offering insights into mechanisms for enhancing coenzyme Q bio-availability. These findings suggest that, with improved delivery methods, coenzyme Q could become a valuable adjunct therapy in the management of diabetes mellitus.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11457790 | PMC |
| http://dx.doi.org/10.2147/DMSO.S481690 | DOI Listing |
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