Media coverage of depression on social media with specific framings could shape people's perception and attitude, which is significant in reducing the stigma and promoting support for depression sufferers. Adopting the lens of moral foundation theory (MFT), this study aims to explore the effect of inherent moral framings within depression coverage on social media on the stigma and approval attitudes toward depression in audiences' responses. A large language model and a dictionary-based approach were respectively adopted to score depression-related media coverages ( = 919) and corresponding comments ( = 92,505) collected from the Weibo platform against MFT's five dimensions and (de)stigma attitudes. The results indicated that care, purity, and fairness framings are prevalent in depression coverage, surpassing moral framings such as betrayal, harm, and cheating. Most responses expressed approval rather than stigma. Moreover, the use of care and loyalty framings can elicit approval responses but decrease audience engagement.
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