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http://dx.doi.org/10.1111/hex.70056 | DOI Listing |
JBJS Essent Surg Tech
May 2024
Radboud University Medical Center, Nijmegen, The Netherlands.
Background: This video article describes the use of bone-anchored prostheses for patients with transtibial amputations, most often resulting from trauma, infection, or dysvascular disease. Large studies have shown that about half of all patients with a socket-suspended artificial limb experience limited mobility and limited prosthesis use because of socket-related problems. These problems occur at the socket-residual limb interface as a result of a painful and unstable connection, leading to an asymmetrical gait and subsequent pelvic and back pain.
View Article and Find Full Text PDFSex Offending
April 2022
USC Keck School of Medicine, Los Angeles, CA, USA.
This study followed 146 sexual offenders released from prison custody for a period of 25-years. Overall, 34% of individuals committed at least one sexual reoffense in the 25 years following release from incarceration. Most sexual recidivism occured within the first 15-years following release.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences University of Campania "Luigi Vanvitelli", Naples, Italy.
Background: Age-related macular degeneration (AMD) is a prevalent cause of irreversible vision loss worldwide, particularly among the elderly population. Two forms of late AMD are described: neovascular AMD (nAMD), characterized by abnormal choroidal blood vessel growth, and atrophic (dry) AMD, involving retinal cell degeneration. Intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents have transformed nAMD treatment, with Brolucizumab emerging as a promising therapy.
View Article and Find Full Text PDFF1000Res
January 2025
Dept. Computer Science, Integrative Bioinformatics, Vrije Universiteit, Amsterdam, The Netherlands.
The solute carrier (SLC) family of membrane proteins is a large class of transporters for many small molecules that are vital for cellular function. Several pathogenic mutations are reported in the glucose transporter subfamily SLC2, causing Glut1-deficiency syndrome (GLUT1DS1, GLUT1DS2), epilepsy (EIG2) and cryohydrocytosis with neurological defects (Dystonia-9). Understanding the link between these mutations and transporter dynamics is crucial to elucidate their role in the dysfunction of the underlying transport mechanism, which we investigate using molecular dynamics simulations.
View Article and Find Full Text PDFOrthop J Sports Med
January 2025
Balgrist University Hospital, Orthopaedic Department, University of Zurich, Zurich, Switzerland.
Background: Identifying hip instability in symptomatic patients with borderline dysplasia of the hip (BDH) is of paramount importance, as it can influence both surgical decision-making and surgical outcomes. The femoroepiphyseal acetabular roof (FEAR) index is strongly affected by the hip adduction/abduction angle during the pelvic radiograph, which has not yet been considered in the recommended threshold values.
Purpose: To compare the corrected FEAR index in symptomatic patients with BDH treated with pelvic periacetabular osteotomy (PAO) or hip arthroscopy.
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