AI Article Synopsis
- - Coumarins, a type of secondary metabolite found in many plants, are mainly produced via the phenylpropanoid pathway and exhibit biological activities like antimicrobial and antioxidant properties that help plants resist diseases.
- - Their antimicrobial effects come from various mechanisms such as disrupting pathogen cell membranes, inhibiting enzymes, and blocking nucleic acid synthesis, while also boosting plant defense responses through reactive oxygen species and immune-related gene activation.
- - The review highlights coumarins' importance in sustainable agriculture, suggesting their use for environmentally friendly pest management and crop protection strategies.
Article Abstract
Coumarins are a specific type of secondary metabolite that can be found in many plants. These compounds are predominantly produced through the phenylpropanoid pathway. Coumarins have been proven to possess a range of biological activities, including antimicrobial properties and antioxidant functions that aid in plant disease resistance response. The antimicrobial effect of coumarins is achieved through various mechanisms. They disrupt the cell membranes of pathogens, inhibit enzymatic activity, and hinder nucleic acid synthesis. Additionally, coumarins stimulate plant defense responses by triggering the production of reactive oxygen species (ROS) and activating the expression of immunity-related genes and signaling pathways such as the salicylic acid-dependent pathway. Due to their crucial role in defense mechanisms, coumarins can be effectively used in sustainable agriculture practices that emphasize environmentally friendly integrated pest management strategies. By providing a comprehensive overview of the biosynthetic pathways, mode of action, and application of coumarins in plant defense, this review aims to highlight the potential importance of coumarins in developing safe and sustainable crop protection strategies.
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| http://dx.doi.org/10.1016/j.toxicon.2024.108118 | DOI Listing |
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