AI Article Synopsis
- - The study investigates the prevalence of bacteremia and patterns of antimicrobial resistance (AMR) in South Lebanon, analyzing 76 positive blood cultures from two local hospitals between September 2023 and March 2024.
- - Results showed an equal split of gram-positive and gram-negative bacteria, with Escherichia coli and Staphylococcus coagulase negative being the most common, and notable resistance to antibiotics was identified, including genes for extended-spectrum β-lactamases (ESBL) and carbapenemase-resistant Enterobacterales (CRE).
- - The findings highlight significant rates of bacteremia and AMR in the region, emphasizing the urgent need for improved antibiotic stewardship and infection control measures.
Article Abstract
Background: Bacteremia is a leading cause of morbidity and mortality worldwide. Rising prevalence and antimicrobial resistance (AMR) are critical public health issues. This study aims to determine the prevalence of bacteremia and the AMR pattern among patients in South Lebanon.
Methods: A cross-sectional study analyzed 76 positive blood cultures from Hammoud and Labib Hospitals in South Lebanon between September 2023 and March 2024. The phenotype and antimicrobial susceptibility of gram-positive and gram-negative were determined by using disk diffusion. Genotypically, polymerase chain reaction was used to detect the carbapenemase-resistant Enterobacterales (CRE), extended-spectrum β-lactamases (ESBL), and methicillin-resistant Staphylococcus aureus genes.
Results: Out of 76 isolates, 38 (50%) were gram-positive and 38 (50%) were gram-negative. Escherichia coli was the most common among gram-negative (18. 42%), with 10.52% ESBL and 3.94% CRE. Staphylococcus coagulase negative was the most common among gram-positive (40.78%), followed by Staphylococcus aureus (6.57%), with 3.94% methicillin-resistant S. aureus. The prevalent ESBL gene was CTX-M (100%), and for the CRE, NDM (66.66%) was the most common gene. Regarding S. aureus, 66.66% were mecA.
Discussion: The diverse bacteremia isolates and resistance genes in South Lebanon reflect global variability in incidence and resistance profiles.
Conclusions: High rates of bacteremia and AMR in South Lebanon underscore the need for effective antibiotic stewardship programs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajic.2024.09.023 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multiple genotypes of Phelipanche ramosa indicate repeated introduction to the Americas.
Am J Bot
January 2025
Department of Biology, University of Wisconsin, La Crosse, La Crosse, WI, USA.
Premise: Phelipanche ramosa is an economically damaging parasitic plant that has been reported in North America since the late 1800s. While this species comprises a variety of genetically distinct host races in its native range, the genetic composition of adventive populations in the New World remains unexplored. On the basis of morphological and ecological variation, some have suggested that the closely related P.
View Article and Find Full Text PDFGlobal, regional, and national burden of primary liver cancer attributable to metabolic risks: an analysis of the Global Burden of Disease Study 1990-2021.
Am J Gastroenterol
January 2025
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Background: The global burden of metabolic diseases is increasing, but estimates of their impact on primary liver cancer are uncertain. We aimed to assess the global burden of primary liver cancer attributable to metabolic risk factors, including high body mass index (BMI) and high fasting plasma glucose (FPG) levels, between 1990 and 2021.
Methods: The total number and age-standardized rates of deaths and disability-adjusted life years (DALYs) from primary liver cancer attributable to each metabolic risk factor were extracted from the Global Burden of Disease Study 1990-2021.
Streamlining Global Germplasm Exchange: Integrating Scientific Rigor and Common Sense to Exclude Phantom Agents from Regulation.
Plant Dis
December 2024
Department of Plant Protection, Biotechnical Faculty, University of Montenegro, 81000 Podgorica, Montenegro.
Article Synopsis
- A team of over 180 researchers from more than 40 countries is addressing the issues related to "phantom agents," which are proposed pathogenic agents that are listed without concrete evidence of their existence.
- These phantom agents, identified only through symptoms and lacking proper isolates or genetic data, create obstacles for trade and plant certification, making effective detection and risk assessment difficult.
- The researchers recommend removing these agents from regulatory lists and updating standards in line with modern diagnostic methods to facilitate germplasm exchange and support global agriculture.
Unveiling the neglected role of the intensity of acute stress disorder in the prediction of full- and sub-threshold posttraumatic stress disorder: looking beyond the diagnosis.
Soc Psychiatry Psychiatr Epidemiol
December 2024
School of Psychology, University of New South Wales, Sydney, NSW, 2052, Australia.
Purpose: Exposure to traumatic events may lead to the development of Acute Stress Disorder (ASD) within the first month post-trauma in some individuals, while others may not exhibit ASD symptoms. ASD was introduced as a potential early indicator to identify those at higher risk of developing Posttraumatic Stress Disorder (PTSD), however, PTSD can occur in some individuals even without prior ASD. Assessing ASD post-trauma can assist in identifying those who would most benefit from intervention to prevent later PTSD, yet the predictive power of ASD varies across studies, with intensity of ASD symptoms and subthreshold PTSD often less considered.
View Article and Find Full Text PDFShared Decision-Making in Total Hip and Knee Arthroplasty: Understanding Surgeon and Patient Perspectives Regarding When It Is Time for Surgery.
J Bone Joint Surg Am
December 2024
Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Background: Although total hip and total knee arthroplasty are highly successful operations, the decision of whether and when to undergo surgery is highly subjective and discretionary, and specific guidelines regarding readiness for surgery remain elusive. The nature of these decisions underscores the importance of shared decision-making, which is founded on the concept that patients substantially contribute to determining their own readiness for surgery. The OPTION survey was developed as a conversation aid to facilitate shared decision-making in the context of total joint arthroplasty.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!