IL-17: A Critical Cytokine for Defense against Oral Candidiasis.

J Immunol

Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology (LCIM), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

Published: October 2024

AI Article Synopsis

  • This commentary focuses on the importance of Th17 cells and IL-17 receptor signaling in protecting the body against oral candidiasis, a fungal infection.
  • The original study discusses the key role of these immune components in mucosal defense mechanisms.
  • Published in 2009 in The Journal of Experimental Medicine, the article emphasizes how understanding these pathways can enhance strategies for combating oral fungal infections.

Article Abstract

This Pillars of Immunology article is a commentary on "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis," a pivotal article written by H. R. Conti, F. Shen, N. Nayyar, E. Stocum, J. N. Sun, M. J. Lindemann, A. W. Ho, J. H. Hai, J. J . Yu, J. W. Jung, S. G. Filler, P. Masso-Welch, M. Edgerton, and S. L. Gaffen, and published in The Journal of Experimental Medicine in 2009. https://doi.org/10.1084/jem.20081463.

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http://dx.doi.org/10.4049/jimmunol.2400510DOI Listing

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